Dietary Cannabis At The Physiologic Dose



Clinical researchers Kristen & William with Cannabis International, and laboratory researcher Yosef Sarne reveal the ultra-low dose of raw dietary cannabis' trace cannabinoid THC, curative and preventative Green Leaf Therapy.  @rawhemp

The official page of Cannabis International has a forum to update your progress and learn from others with your condition! Visit them here https://cannabisinternational.org/wordpress/

"The totality of life is in the hands of raw cannabis."
"Cannabis is not a cure for death. It is a celebration of life and health."
"Disease arises at the cellular level. Cannabis supports cell health - if you are willing to use it in a respectful fashion."
"This plant: we can't even imagine what thirty million years of collateral evolution means.
But it is a pinnacle of enormous, enormous amount of effort.
And the last thing it needs is for humans to come along and completely invert the chemistry and the ratios."




To learn about the benefits of dietary cannabis all encompassingly mutes paranoia towards THC. 
From dietary essential for everyone, to a therapeutic essential for those with compromised immune systems and failing health; Cannabis as a vegetable promises to end the era of epidemic disease.


Please copy, share and share again! Quotes and other content have appeared in many unbiased articles!


Here I teach about immune modulating activities and non-psychoactive properties of raw dietary cannabis - the basics of up-regulating the immune system with a vegetable capable of down-regulating our immune system!
This is a volunteer project on behalf of the research of Kristen Courtney & clinician William Courtney, M.D..

The option to sprout hemp seeds is new: Viable Biona & Hempo brand seeds made available on Amazon or hemping dot com (either may ship to your country). 
Please mix these with sprouting seeds if you live in a zero-tolerance state - this is an opinion of the author and not quoted from any clinics! Although a great food source, 12 - 14 day old sprouts may not be as effective as growing bonsai plants for leaf.
See tutorial below!

To understand the plant as an evolutionary gift will end Prohibition. The seed shell carries Cannabisin B, a protien with powerful anti-neoplastic activities.
The seed achene & oil provide GLA, which our body turns to CLA; for use as cholesterol, hormones and endo-cannabinoids.
Sublingual and suppository hempseed oil retaining activates the vagus nerve and removes stored toxins.
The trace THC available in any form of Cannabis vegetation acts as an anti-inflammatory in the broadest of spectrums.

By lowering the amount of fat needed for the bodies own cannabinoids, you can reduce the amount of prostaglandins created in the process.
The liver processes dietary THC into 11OHTHC, acidic cannabinoid which is active at GPR55 (although it is psychoactive).
If you eat excessive lipids, without properly expending them through excersize, the body creates excess lipid tissue stores. This slows down metabolism.
In the same way, consuming too much of the exogenous cannabinoids creates a burden for the body to create more receptors. As the anandamide which is naturally created for your receptors is switched back to a fatty acid, the prostaglandins build up.

By only eating the Cannabis you need, a few leaves each browsing session, you reduce natural anandamide levels with the prostaglandins; and keep the immune system tip-top for the best metabolism and a liver processing hormones normally.

In summary, dietary use, the way animals use the plant: Provides trace THC, which activates ALL of the bodies CB1 receptors, matures the immune system's dendritic cells, neuroprotective & adaptogenic at COX-2, increases neural blood-flow, hepa-protective, reduces inflammatory prostaglandins, and proliferates healthy tissue via ERK signaling; terpenes (especially beta-carophyllene) are active at CB2, mood stabilizing, promote neuro-genesis, and maintains stem-cell health; as a mere one day old sprout, without 'detectable' cannabinoids* Cannflavin forms, to inhibit prostaglandins and other inflammatory metabolites; as a 12 day micro-green, acidic phyto-cannabinoid-rich hemp-grass may be the best oral health dentifrice, the young taproot fiber creates butryic acid in the gut & carries multitudes of compounds good for circulation, and a high acidic cannabinoid/total weight ratio of older sprouts activates GPR55 which is anti-spasmodic and controls inflammation from bad cholesterol.

'Corporate' use of the flower causes a reduction in blood-flow to the brain; dulls the immune system response to proliferating tissues; burdens the liver with estrogenic compounds.

As Dr. Bill says: 'We are optimizing every cell in the body with the raw plant.'


In seven years of patients 50 of Cannabis International's patients are in remission, after eating vegetative cannabis leaf - Green Leaf Therapy. 
In this time 150 other conditions were also successfully treated!
They now contend dietary cannabis is essential from conception thru senescence!

The vegetable, from sprout to mature leaf, has been termed 'fabulous food'. 
"As opposed to our previous interest in taking a single molecule out of 150, and consuming 30, 40, 50,000 micrograms of that when the animal kingdom is doing twenty or thirty.
As we look at how other animals use and benefit from this living plant across the year, there is a lot to learn about our own health maintenance ability to prevent disease.
And the ability to deal with trauma, surgery, incisions, healing and repair. As well as recovery from conditions we may have found ourselves in."


The best medicine: Chew three to five vegetative leaves during a few browsing sessions; every day or other day.
This small 'bite' delivers 20 - 50 micro-grams of Delta 9 THC - with a spectrum of healing compounds. 


Bill and Kristen Courtney have taken a Hippocratic oath for some 8,000 patients; while publishing abstracts that advocate research on conditional, geriatric, oncological, maternal, pediatric and prophylactic whole plant cannabis applications.


"And now we know that this GPR-55 receptor is part of the nuclear membrane, we know that it is found on the mitochondria; we know it is found on the endoplasmic reticulum, and on the lysosomes and endosomes. And that the acids are the molecules that act at that site."

"So, you know, if every animal eats this raw plant; and if they use a small amount of leaf; and, you know - if we can come to a consensus on the amount of THC in the leaf - and that amount has been corroborated by the ultra-low dose studies; the next question is: Why would our president come out against raw cannabis?
From my perspective it is probably the single most important food substance on the planet after water."


In a interview titled "the Ultra-low Dose' Yosef Sarne's series on the 100 micro-gram doses are discussed. He found an important enzyme inhibiting COX-2 was altered to remain inside the cell for seven weeks; before a new one is formed and replaces it - significantly reducing prostaglandin production.
Sarne's first paper was on neuro-protection. After being impressed with those findings, he went on to the heart, then liver.

The THC we collect in fat stores by eating a couple leaves builds up to the 100 microgram dose; we are protected from ischemia, MDMA toxicity, seizures, inflammation, anesthesia, brain injury - for weeks after a dose.
100 mcg is apprx 1/100 of a psycho-active dose. 


Children with epileptic conditions can benefit from the protection without becoming intoxicated.

In the animal kingdom, there are 7 week periods where leaf may not be available, but the body has a store of THC to keep COX-2 inhibited.


To better understand how an enzyme which inhibits COX-2 receptor expression is beneficial: promotes lucid dreams; balances the Hypothalamic - Pituitary - Adrenal axis; and lowers cortisol. 
Other herbs which share this activity (although not as long-lasting) are Ginseng, Cistanche, Ashwaganda, Magnolia, and Lemon peel. 




The Leaf documentary


Cannabis International Foundation has been supporting the whole plant since 2007; both in the clinic writing leaf juice prescriptions, and standing up at conventions to speak on behalf of the vegetable - when often "THC" is assumed for "cannabis".

By eating the leaf, mankind and any browsing animal protect major organs - not to mention oral health benefits!

This targeted cannabinoid therapy is 
essential during pregnancy, and for any individual between conception and senescence.
Patients of age 30 or senior, and those with compromised immune systems may need Green Leaf Therapy as a therapeutic essential.

34 million years of co-evolution, mankind originally had eaten raw cannabis along with every other vertebrate. It seems we have continuously learned, from deer and local animals, to eat a few vegetative leaves at our meals.
Rabbits and some cud-chewing cattle learn to limit intake - the secondary stomach in the GI tract may cause any THCa to become psychoactive THC.

Chewing the plant promotes oral health; and has no loss of valuable cannabinoids, as would occur with blenders and juicers. 
The liquid retained on the walls of a blender carry a great percentage of the trichomes from plant material.

A group of Israeli researchers produced a metered inhaler device able to supply this 100 microgram dose 'SYQE'. 
This is the first time that pulmonary application became an option for a physiologic dose.

Since we know THCa does break down in the dry plant slower if stored properly, recreational cannabis may be ground as kief and eaten, for the physiologic dose. 

If you already use cannabis infused cooking oil consider reducing the potency, by adding more oil.

Abstaining from anything high-THC during this dose will allow your GI tract 4 hours to absorb what you need, for enjoying the Hygieia effect! 

When juicing cannabis optimally we only use leaves. 
Flowers may have significantly greater trace Delta 9 THC; and consuming any amount may prevent delivery in the micro-gram scale. 

After a course of three months using the plant as a dietary essential the body may reach a point of tissue saturation with cannins!


"If you have not eaten cannabis for a long time, you are struggling alone: Your immune system is doing it's best - but, it's my belief that if the CBD was there 5 years ago, or 20 years ago - if it was part of your diet daily, there would be a lot less of those cancers that we then would have to struggle with, in a life and death fashion. You want to have CBD present before an event occurs. So, if you are eating leaf regularly, and if your CBD content is ready - think of it like Vitamin C: Its just an anti-oxidant on board. You limit the extent of the re-profusion injury, and you mitigate the damage from being done."


"It has captured these molecules that help our bodies regulatory systems be more effective. The bottom line is, its a dietary essential that helps all 210 cell types function more effectively. I don't even refer to it as medicine anymore, strictly as a dietary essential. Used as the dietary essential that it is, there is no need to call it a medicine."



“I believe this plant, having evolved over millions of years, is put together to support that system"


A 1:1 CBD:THC may have better psycho-activity than a low CBD chemotype.

The best example of using 1:1 medicine for health might be Moroccans, with dozens of cultural uses of hash.

"Morocco may be the only place on the planet where men live longer than women. The cultural aspect is that men sit around and smoke this hash together that is 40-50% CBD. And so, by accident or societal prudence, they are consuming a significant quantity of these 'prophylaxis' cannabinoids, and it appears to have given them a capacity to weather the rough lifestyle and add years to their lives."


"Cannabis is an incredibly complex, synergistic plant whose constituents have yet to be completely catalogued - yet alone understood. Until that time, which will not be any time soon, it is the individual who can best identify the specific plant phytogenetics / chemotype most suited to assist them in the preservation and restoration of their health. Once the ideal cannabinoid profile has been identified, then that ratio is tried in a number of plants i.e. Indica, Sativa, Ruderalis as a beginning point in assessing the contribution of various terpenoid profiles."


Historically, raw dietary cannabis applications were intended to sharpen mental clarity, or aiding organs of elimination.

''A child who used to have hundreds of seizures a day now goes days without having a seizure. Another patient of mine who is 2 or 3 years old had a brain stem tumor. After receiving 10 times the fatal exposure of radiation and a bone marrow transplant, she was sent home from hospice care. She was consuming up to 4 - 8 oz of raw cannabis juice per day: Her MRI came - not only is the tumor gone, but the radiation damage (the scar tissue) has completely reabsorbed in a year and a half; and it normally takes 5 - 6 years for that to reabsorb.''


Dr. Courtney and his wife began juicing cannabis daily, after experimenting with eating fresh, raw cannabis.

For many years, Kristen struggled with systemic lupus. 
When her condition improved dramatically following several weeks of saturation with raw cannabis, they were convinced they had discovered a cure for chronic illness.

Kristen shares, "You wouldn't consider a diabetic addicted to insulin. I have an Endogenous Cannabinoid Deficiency. When I drink the leaf, I feel more attentive, more awake. I can breathe better. I don't get heartburn or stomach pain, or feel muscle weakness or lower back or pelvic pain. By eating it, I am able to saturate much more so than I could. Even if I was smoking all day long, I wouldn't be able to saturate as heavily as I can juicing. I think the anti-fungal and anti-bacterial which is CBN, and the THCa and cannabidiol are all helpful. But I think, more importantly, it is the interplay of all the cannabinoids together that causes the most benefit. That when you isolate each one and take it alone, or take it as a pure synthetic it can't have the benefits. It doesn't have the same effects that they all have together. I thought: How does everyone not know about this. I felt right then and there my focus in life had to be helping other people in my same situation to get this information to use as well."

Both Dr. Bill and Kristen share the joy of helping others with raw cannabis: "It makes you feel good when they come back, and they have stopped using something that causes GI tract bleeding or causes liver damage, pain pills and anti-inflammatory drugs. You feel like it's worth the whole struggle to get the education out there."

Cannabis can replace many, many of the most prescribed pharmaceuticals: Kristen was given forty such medications, before seeing health stabilize with cannabis juice (homeostatin). 

NSAIDS like Aspirin, for example are involved with increasing endocannabinoids - with toxic side effects. 
Alternatively, THC raises anandamide; and CBD has the same methylating activity, to keep blood viscosity tolerable in a pulmonary disease condition.

Another market, pure isoflavone pills and synthetic estrogens are replaced with hempseed sprouts, with a potent estrogen receptor agonist, cannflavin. Even more potent, Hops, a cousin of Cannabis has the strongest phytosterol - 8-PN. This isoflavone is also known as xanthohumol and hopien.


Juicing Cannabis for Healing: How I Achieved Almost Complete Remission of Chronic Pain by Juicing Fresh Raw Marijuana Leaf

Katie Marsh, one of Dr. Courtney's patients starts her day with a green leaf smoothie; blending yogurt, fruit and thawed, juiced cannabis.

“To drink it straight is kind of bitter, but it’s not at all objectionable in a smoothie,”

Marsh is diagnosed with severe rheumatoid arthritis, causing painful swelling in the hands and feet. 
She was prescribed pharmaceuticals; but chose to keep her internal health - and sought a natural remedy.

“It got so bad that I had trouble getting out of bed, getting off and on the toilet and even dressing myself." 

As a Californian, Marsh chose the option of cannabis applications, such as smoking for pain relief.

When a friend suggested juicing leaf, she took to the idea - as she'd previously started juicing wheatgrass.

After a prescription from Dr Bill's office, she obtained a bag from a grower and started juicing it every day.

“I saw results very quickly. Within a matter of a couple of days I was able to stop the prednisone and ibuprofen.” 

In one year of juicing cannabis, Marsh has control of her symptoms.
She is turning to topical cannabis to rejuvenate damaged tissue.

Her book "Juicing Cannabis for Healing,” described a journey with the plant, finding access and relief:

“In my ideal world, it would be nice if one day you could go to Whole Foods and buy it in the frozen section."

                 



A growing need for access to organic cannabis for therapeutic applications

If you live near medical or recreational gardens, ask for organic leaves: Gardeners remove pounds of fan leaf per month. These leaves may either be washed for hash, which can then be reused in juice; or the grower will have it composted!
As a patient, one may find many caring growers in your state at online forums. 

Many caregivers have begun to provide leaf to patients; as well as frozen juice, often immature flowers or mature leaves which needed to be pulled.

Dried and properly stored (from harvest to one yr) flowers may still have most of the acidic CBDa and THCa intact.
A guide at www.epsilonreasearch.org created for patients to use dried flower for acidic, or partially activated tinctures. Epsilon Apothecary will help you create a tincture with acidic cannbinoids - child safe dosages and a much longer shelf life than raw or dry vegetation!

Common Hemp seed oil provides 10 mg/kg CBD, 0.6mg THC per 50-100 ml and traces of acidic phyto-cannabinoids.
Some EU or CA sourced Hemp seed oil contains up to 50 mg of THC per kg.

Swiss hemp essential oil contains 540 mg of CBD and 3 mg each CBD, CBG and CBN per kg (Composition of hemp seed oil, C Leizer).

To treat a condition with cannabis, please consult with: www.CannabisInternational.org or www.EpsilonResearch.org 

These are a few dispensaries supporting juicing: Arcata Humboldt Patient Resource Center, the San Jose Canna Culture Collective, the Mendocino Leonard Moore Co-op, the Denver RiverRock Wellness, the Kalamazoo Med Joint Community Compassion Center, and the Olympia Sonshine Organics Network. 

Some patient networks for local leaf are Cannasqueezed & Grow Hemp Project in Northern Colorado; and Grass in Northern California.

These vendors ship raw cannabis juice, smoothies, oils and pills:
Cannasqueezed freezes cold pressed organic juice, with the whole plant - leaf to root. She will deliver OR ship overnight (50 states, no THC) http://cannasqueezed.kickoffpages.com

CO2 THCa oil very lab quality www.kushresearch.com 

Smoothies and shelf stable pills, possibly California only www.Cannamin.com

Sanahemp juice and Grow Hemp Colorado are sources of local hemp juice, for Netherlands and Colorado.

Tinctures and topicals are art perfected in our homes! http://spagyricapothecary.com hemp tinctures have un-paralleled absorption in the GI tract.
Topicals should include whole plant extracts, cold pressed oils (or Emu oil) and essential oils (or DMSO). 







Treating Cannabis like a Vegetable


For those who can grow cannabis, plant a seed or clone each day; and keep it in 12/12 flowering to rapidly mature a bonsai. 
Some patients who grow hydroponics use bonsai plants for each root ball.

Roughly 30 leaves, or 6 grams of leafy greens create a good blender smoothie.

Whether blender smoothie or fiber-less juice, the freezer is a good place to store cannabis juice for tomorrow. 
Containers of plastics and glass left holding a cannabinoid solution seem to compromise potency by allowing a surface for these 

Leaf should be eaten in the vegetative stage; while trichomes are clear or milky.

Eating whole leaflets is easier on the branch, compared to each time you remove a fan whole. 

Eating a fresh bud means more chewing for the patient, but is the only way to deliver 100% of the medicine, and is recommended for any advanced condition.

To prepare leaves for a juicer, soak in a bowl of cold water for 5 minutes (adds moisture to the hemp, for more juice). 

Make sure not to rinse the leaf, this would wash off trichomes.

Make sure the leaves are entirely clean before the soak - even if they are organically grown.

Coconut oil may be added, to lubricate leaf going through masticating herb juicers. Coconut water is also an option for soaking the leaf.

Bill and Kristen had been mixing carrot juices 10:1 with leaf. Today, Kristen may use any blend of "Whatever is around."; mangoes, lemon juice, turmeric, ginger, kale, broccoli, beets.






"It's the poster-child for raw food."

"You can use it in the morning and midday, still function - drive cars, there is no interference with your ability to take care of your daily issues."






HEMPGRASS!
Eating sprouted seeds has tremendous mood stabilizing activity; can be blended for a miracle healing mouthwash; has some of the best compounds for elderly conditions and mothering. 
Although a great food source, 12 - 14 day sprouts may not be as effective as growing bonsai plants for leaf.

CBG is the first 'mother' cannabinoid, in Cannabis Hemp sprouts by day three (Marijuana Chemistry, Mike Starks).

Around day 7, the young sprout is a nutrition warehouse. 10 days, 12 days and 14 day old seedlings are increasingly covered with trichs; will be nearly as potent as an adult plant in weight/trichome ratio.


To grow yours, first soak in glass, ceramic, or unfired clay overnight. Spread over soil or media mix. A three inch layer of medium is plenty; a small pinch of seeds is about 80 sprouts. Soil or medium can be sand, peat, or coconut husks. 
The important part is drainage, and a good space for roots to grow in. First filling a smart pot or breathing container with clean rocks and pebble allows the medium, on top, to drain; and encourages very long taproots.
Keep the soil moist until the sprouts arise! 
Once the party started, water every other day to keep mold off and encourage growth. 
Sprouts like light, especially white and blue spectrum. Deeper reds also raise CB total; for a very noticeable sensation of the trichomes on your tongue, when eaten.

One pound of viable seeds will yield 3 pounds of sprouts.

Remove and clean un-eaten grass from soil and refrigerate after day 14. Please eat them fresh!


The best value for small quantity, Biona seeds on Amazon. Prices change, today this two-pack is the best value. Order as many as your community may need: http://tinyurl.com/jjsqlph

If you would like a larger quantity of seed with a known variety: Hempo brand provides Bialobrzeskie & Fedora 17 http://www.hemping.com/viable-hemp-seed-whole-1-kg




Risks to Avoid with Dietary Cannabis

Plants sprayed with any pesticides shouldn't be eaten; although some pests are edible, like spider mites.

This complaint published on a health e-zine is not a health risk: "The throat irritation is based on the fact that the stems of cannabis have sharp little hairs" from Why the raw cannabis juicing trend may not be all it's juiced up to be -Xeni Jardin.
In a narrative of Superfoods: The Food and Medicine of the Future - David Wolfe said "Hemp leaves contain a high percentage of silica and fiber. One side of the leaf is soft and the other side is abrasive, so as the leaf is eaten and the fiber moves through the body, the sides of the leaf churn through the tract, scrubbing and softly cleaning the intestines."


"If you heat the plant, you will de-carboxylate THC-acid and you will get high. You'll get your 10 mg (of THC). If you don't heat it, you can go up to five or six hundred milligrams, use it as a dietary cannabis and push it up to the anti-oxidant and neuro-protective levels which come into play at hundreds of milligrams. It is this dramatic increase in dose from 10 mg of psychoactive THC to the 500 mg - 1,000 mg of non-psychoactive THCA, CBDA, and CBGA that comprises the primary difference between traditional ‘Medical Marijuana’ and Acidic Cannabinoid Dietary Cannabis. However, other compounds in the plant, such as terpenes, may have an effect on mood or energy levels." 


About one in 1,000 of Courtney’s patients had a psychoactive smoothie, in recipes with both the leaf and the flower. 
This combination may make the smoothie much less effective as an anti-inflammatory for the patient.

Allow your electric juicer to cool when running lots of leaf: A hot cannabis soup could potentially equal the THC in tens of joints. 

A hot grow lamp, or extra heat from the sun on a mature bud may also mean more THC in your raw cannabis.

Terpenes in raw dietary cannabis are the sedative volatiles; they could be considered mood altering. 
A medicinal terpene application, sniff a whiff of ground buds before vaporizing.


Pharmacological Effects of Raw Cannabis

Patients found the juice lowered their blood pressure an average of 10 points within 2 hours.


Patients with arthritis have used fresh leaf as topical anti-inflammatory, placing ground leaves over the affected joint overnight.


While CBD gets across the blood brain barrier, CBDa is twice as bioactive; and with THCa, guides immune modulation.

Medibles also saturate: after the liver converts THC to an acid metabolite, 11 0H THC - this acts as THC acid on the CB3 in the cell memrane & cell organelle.


Food grade oils are prepared by caregivers for a patients health, specifically.


The ratio of CBD:THC (CBD ranges .4 - 24%) suppresses enzymes that allow THC to cause psycho-activity; also modulates how the THC ligands distribute at CB1.


Excersize raises (and alcohol lowers) the concentration of serum cannabinoids.


"Anxiolytic: If you highlight it every time the federal patent refers to anti-anxiety effects, in a somewhat humorous effort to distinguish anti-anxiety as a non-psychoactive effect.. And as a psychiatrist, it's like 'Ha, they're trying to distinguish the THC effect from the CBD effect!' - "CBD really helps with anxiety - that's OK. THC - we don't know what it does, but that's horrible"!







Dr Bill's Recommendations:
Kief the bud, then add it to yogurt.

Dried trim Leaf: Baked goods or Shona Banda oil (higher in THC use in edibles).

Topical: Use oil to extract the cannabinoids (THC, CBD, CBC, CBG, CBN). Fill bottle with bud and or leaf then cover with oil and shake for 2-3 weeks. Filter off the plant material. Use as a topical massage oil for local pain, muscle spasms/articular inflammation. Alternatively, add 1 gm kief to 2 ounces of melted salve and dissolve. Apply locally, increasing test dose strength gradually.

Tincture: Use edible alcohol, cover the bud/leaves with alcohol, can crush/stir the mixture only done for minutes you will primarily get cannabinoids. If done longer, you will increase the amount of chlorophyll.

Other topical uses: Leaf powder can substitute for sugar/salt or apricot seed as an exfoliating skin rub. Hemp seed oil has an SPF 6, and softens skin/hair.





"If there is a word I would choose for my tombstone that would summarize the last six or seven years, if not the rest if my life, it's the clear vision that cannabis as a plant, with all of its incredible synergy is a homeostatin for animals. You have two parts of the carbon cycle: you've got the plants that take in CO2 and produce sugars and food and exhale O2: so you have the plant and animal as two parts of this integrated carbon cycle as complementary aspects. What is that relationship about? Why would a plant produce 120 carbon molecules that primarily regulate the intra-cellular environment of the animal?

The animal takes that oxygen and mixes it and produces CO2. They go back and forth and why would a plant spend such an incredible amount of energy to produce these molecules that supports the physiology of the cell?

And now we know that this GPR-55 receptor is part of the nuclear membrane, we know that it is found on the mitochondria; we know it is found on the endoplasmic reticulum, and on the lysosomes and endosomes. And that the Acids are the molecules that act at that site.

When we take the plant - the cannabis - and heat it, then you lose that interface.

The homeostatin is a molecule that supports homeostasis and the restoration of optimal function: it takes the over-active cell and down-regulates, the underactive it up-regulates. The homeostatin is the molecule that mediates homeostasis and its complement in the world genome.

And so there is this very very deep relationship between the plant and the animal. And l believe its primary role is the optimal function of life on the opposite side of the pole. An interface as beautiful as a relationship can be."











Clinical Research:



Whether Sativa, Indica, Ruderalis, male, female, hermaphrodite, native, feral, bred for fiber, seeds or medicinal resin, Cannabis is the best source for the multitude of anti-tumor activities of compounds D9THC, D8THC, CBD, CBG, CBC, D9THC-a, CBD-a, CBN, varins and terpenes (over 500).

Male and female cannabis plants have similar cannabinoid potency throughout development (Marijuana Chemistry, Mike Starks).

"If you look at a drug like Marinol, the problem is 50% of the Marinol is not biologically active; 50% is Right-handed, 50% is Left-handed... Only one of those can fit into the receptor in the body and alter the cell physiology. And - the one that's very similar (it has the exact same number of molecules but not quite the same shape) actually can interfere with some of the functioning in terms of blocking binding at the receptor site in the receptor, in what they call the orthosteric binding site."


The Dr. explains, "The body produces endogenous cannabinoids. You may have heard of endorphins: that's endogenous morphine. Well, in a similar fashion, the body produces endogenous cannabinoid."

"A million times a day, cells begin to divide that shouldn't be dividing, and the immune system has to say, 'Hey, you know the shrubs are getting a little hairy there; we've got to trim them down. We've got enough renal cells or kidney cells. We've got enough bone cells, muscle cells'. So the immune system's highly competent at dealing with that, but it can become more competent. That is exactly what cannabinoids do, whether you're talking about the body's endogenous cannabinoids, or the plant, which can be phyto-cannabinoids or exogenous cannabinoids. Both of those terms (phyto-cannabinoids and exogenous cannabinoids) refer to those twenty carbon molecules produced outside of the body, but bind to the protein receptors on the cells in our body and therefore, help regulate it. So whether, we're talking about the body's chemistry, or the plant chemistry, their role is to modulate the function of the immune system."

"So”, the doctor adds, “a cannabinoid is a modulator that restores optimal function. That's what the body's system is doing. That's what the plant does. The plant facilitates the rapid restoration of the normal function."

Our receptors also use ligands from terpenes like b-Carophyllene; EGCG, catechins found in plants like green tea; ketones, in raspberry leaf (or produced by a breakdown of fats); as well as fatty acids DHEA and EPEA for regulating endocannabinoid function (the system described as the root of all health). 




Clinical Cannabinoids: CBD

When 5 mg/kg of CBD is indicated for one's condition, a patient may need to remove THC to allow a higher quantity to be tolerated (unless a pure CBD strain is available).

"Take your cannabis. You grind the cannabis to a fine degree which increases the surface area so that you can get to the cannabinoids in the plant material. You get a variable temperature heat gun, which allows you to provide a constant single temperature for hours at a time, so that it's better than any of the vaporizers, because it's very, very, very steady. You turn the heat on until it goes to 166 degrees Centigrade. The longer you heat it the more THC is boiled."

D9THC boils at 157C. D8THC boils at 175C. CBD boils at 160-188C. CBD Diary – Project CBD informs, "However, both begin to sublimate off at even lower temperatures, and commercially available vaporizers, even the Volcano, do not heat evenly enough to allow fractionation of one component over another. What your patient is doing is wasting some cannabinoids and terpenoids by preheating. To get all of them out requires more prolonged heating, or a higher temperature. When the latter is done, it favors higher molecular weight sesquiterpenoids, many of which are sedating."

In one study, an electric vaporizer was shown to release substantial amounts of the THC while producing no benzene, toluene, and naphthalene, which are generated when cannabis is combusted.
"Analysis showed that the Volcano vapor consisted almost entirely of THC (95%), with traces of cannabinol (CBN). In contrast, analysis of the combusted smoke showed a potpourri of at least 111 different gas phase components, including six known PAHs. Non-cannabinoids accounted for as much as 88% of the total gas content of the smoke." O’Shaughnessy’s, Summer 2003 pg. 9

CBD is present at 4,500mg/lb in Northern Lights, a 1% CBD, and new 5% strains provide 22,000 mg/lb. The ideal CBD dose to body weight is 5-20 mg/kg. 

For a 200kg person to reach a 5mg CBD dose, it would require 500mg of a 5% strain.

CBD is a lipid anti-oxidant stronger than Vitamin E.
It's useful in the prevention and treatment of oxidative conditions such as amphetamine or alcohol exposure and diseases of the CNS as it crosses the Blood-Brain-Barrier and exerts anti-oxidant activity.
 Furthermore, sedating, hypnotic, anti-epileptic, and anti-dystonic activity has been detected.

William L. Courtney elaborates, "So, it's a fat molecule that can get into the brain, which is very hard to do because the brain is very protective, but because this has 34 million years of research on its side it knows how to walk between the lines and the body has allowed it access to the brain. So, for Parkinsons, for Alzheimers, for strokes whether embowelic, hemmorhagic, or traumatic, or surgical, these are all conditions where CBD is uniquely beneficial."

Some CBD rich plants are: Industrial Hemp; strains that were bred a few decades ago that remain as they were in the 60's-70's; plants from sohumseeds.com, cbdcrew.com, and labs such as GW Pharm.

"The Hemp plant is actually an excellent plant because the THC content can be low, that's if you're treating a condition for which appears CBD food supplement is in order. The plants we're using in Luxembourg have only 1% CBD, a 1% CBD plant is providing you with 19 times more CBD per pound than Oranges provide you of vitamin C. A 1% is an excellent source, you can make tremendous concentrates, you can eat the plant raw; and in the absence of the THC you can heat Hemp, which you can't do with other strains because the THC acid comes out and you end up with a psycho-toxic substance."— William L. Courtney, M.D
  


Clinical Cannabinoids: CBN

CBNa (cannabinolic acid) is produced naturally - at maturity (as THCa ages); and CBN as THC decarboxylates.

Listed activities of CBN are: sedative, anti-leshmanial, antibiotic, antibacterial, antifungal, anti-convulsive, anti-proliferative, able to decrease intestinal motility, and CBNa has regenerative activity at the stem cell.

Shona Banda Oil cured in a sun-lit container may concentrate CBN.

Resin, or reclaim oil, carries less THC than smoke, and possibly 0.3% more total CBN and CBD.

Bong-water has no cannabinoid content; without an addition of alcohol or fats. (Marijuana Chemistry, Michael Starks).










The 17 Sisters of Mercy:

Growers in Northern California, working with the clinic have found that hermaphrodite seeds express unique cannabinoid ratios from the various genes chosen in attempt to survive the species.

The Sisters of Mercy are 17 different female seeds from a hermaphrodite (self-pollinated intersex)  Cannatonic.

Each range between low THCA /high CBDA, the various ratios can apply specifically for an individual's condition.

"There is tremendous drive within this plant to survive the winter. Stressors like light, heat, hydration, chemicals; anything that really pushes the plant will force it to make it's last ditch best effort to survive.
Then, suddenly, feminization was not just a horrible human intervention; it was this plant stating "Wow! This is a rough environment and we need to put our best foot forward.!"
And in doing so, it may throw it's wildest cards down on the table.
So, despite all the huge negatives of hermaphroditic changes, the fear "All feminized seeds are going to select for hermaphroditic and we must steer clear of them! " the hermaphroditic tendency is a survival tendency.


Quotes from the Clinics: 


"Use of the raw plant includes the acid cannabinoids; CBDA, THCA, CBGA, CBCA.

The acid cannabinoids, CBDA and CBGA are now known to act at GPR55 as potent antagonists of that pro-inflammatory receptor.
The acid cannabinoids are 2-4 fold more effective than the neutral cannabinoids, which have been the exclusive focus of study for the last 30 years. 
The neutral cannabinoids (CBD, THC, CBG, CBC) are functionally synthetic molecules made by application of heat to alter the naturally occurring Acidic Phytocannabinoids. 

The specific ratio of cannabinoids is an area of tremendous significance and an area in need of additional research. 

Consumption of the whole mature raw flower / bud and leaf is the best current thought. 

The amount per day is dependent upon the weight-to-weight cannabinoid content analysis of that specific plant as there is dramatic variation between particular plants of the same name and across time for a specific plan

If analysis is not available, assume high THC concentration in the 8% to 21% weight to weight or w/w. 

In general CBD is usually less than 1% w/w. 
Another way of describing the relative amounts of THC to CBD is cannabinoid content. 
For the vast majority of strains in California the ratio OF CBD TO THC per 100 grams of cannabinoid, is 0.4 to 1.0 grams of CBD/100gm to 90-95 grams of THC/100gm.

Sadly the other 78 cannabinoids share the remaining 4 grams. 

Note that W/W is the amount of CBD per unit weight of cannabis where cannabinoid content is an estimate of the relative amount of THC, CBD, CBC, CBG, CBN etc per 100 gm of cannabinoid extracted from a particular strain.
Individuals often start out with 1-3 grams of mature bud / flower to assure no idiosyncratic allergic reaction or psycho-activity. 

In indoor grow rooms with low ceilings sometimes the buds get very close or touch the high pressure sodium lights which are hot enough to breakdown THCA into THC. 
It has been suggested that very hot outdoor grows may also have some decarboxylation at the top of the plant but this is very rare.

 Once comfortable with mature raw flower, slowly increase the amount to 14 grams or 1/2 ounce wet weight mature bud harvested from the living plant. In addition to the raw bud use 30 to 300 leaves per day in accordance to the amount of plant that can be consistently provided on a daily basis.

 It is best to juice the leaves to decrease bulk of the fiber but it is best to blend the flower into the juice of the leaf, particularly with the new 10-20% CBDA strains. 
Blending the bud rather than juicing it, reduces the loss of cannabinoids that adhere to the ejected fiber that is part of the juicing process. 
In the past bud was juiced when using 1% CBDA plants because of the large amount of plant material required in order to recover 600 mg of CBD.
Flavor management is a very important for compliance.
The juiced leaf and blended flower is combined with hemp milk/ hemp oil / keifer / yogurt into a smoothie or combined with fresh vegetable or fruit juices. 
Organic produce without the fungicides, herbicides and pesticides are important if available.

The smoothie / juice with its phyto-cannabinoids / terpenes / flavinoids are best taken in divided doses due to their rapid clearance i.e. the cannabinoids clear in about 50 minutes after absorption from the intestine is complete. 
If the final amount is 10 ounces, then divide into five 2-ounce doses and take every 4 hours. Keep on ice. 
Shake before using to mix the fatty acids with the water portion of the juice. 

For serious illnesses, try for 6 doses a day, that is leave one dose in the refrigerator for consumption if one gets up to use the restroom at night.

Replace high THC plants with plants of increased CBD content and ideally with plants providing specific ratios of CBDA to THCA indicated for the specific medical condition.

The THC dose, for those that are comfortable with THC, is 10-15 mg. If you are blending a mature bud into a glass of juice it could and should have 5-600 mg of THCA and 5-600 mg of CBDA if the plant is a 1:1 plant such as the original Cannatonic 6.9%w/w CBD to 6.2% w/w THC or a tested strain of Harlequin, which range from 4%/4% to 8%/8% CBD/THC.

If that juice is accidentally heated by placing the ‘vegetable’ juice into a vegetable soup, it will create a very psycho-toxic dose of THC.

Reiterating to a fault, if you are consuming 600 mg of a 1:1 plant, you are consuming not only 600 mg of CBDA but also 600mg of THCA, upon heating the THCA turns in to approximately 580mg of THC when the tolerable dose is 10 mg! That would be like consuming 58 brownies when you can only tolerate 1!

If you find a source of Cannatonic seeds beware that the Cannatonic feminized seeds can vary widely from the original plant. 
Recent HPLC testing showed an expression of CBDA from 22% w/w to <1%CBDA and concurrently THCA contents ranged from 1% w/w to 30 % w/w. 

This marked divergence mandates testing of the plant while keeping back living clones in case you locate the desired cannabinoid ratio."



"The fact that such a prestigious institution as the National Cancer Institute has acknowledged that there are direct anti-tumor effects, means that at the top things are beginning to change. But that will have a double-edged sword: If cannabis really is that beneficial, let's get out there and make it Roundup Ready, and grow it cheaper ,and make sure it's sterile seeds.. so you have to buy it from Monsanto. So people can't propagate it on their own. It's the next wave: If it's not basically illegal the world over, then let's make it inaccessible - unless you buy from a company that owns it's genetics."
— William L. Courtney, M.D


"Over 525 different chemical compounds have been identified in the Cannabis plant. These substances act as primarily feedback modulators facilitating the Endogenous Cannabinoid System’s regulation of cellular physiology. The plant’s primary constituent is THC-a, which along with other phyto-cannabinoids, interact to modulate the immune system.

Patients become dysphoric or euphoric on 10-20 mg of THC, well before they can take in a full dose (200 to 1,000 mg) of the other non-psychoactive cannabinoids. Many middle-aged patients cannot tolerate THC, even if it alleviates their symptoms, due to the dysphoria that interferes with their day-to-day functions. Age or heat decarboxylate THCa to THC, reducing the tolerable dose from 2000 mg to 10 mg, and resulting in the loss of the inflammatory, anti-spasmodic and anti-proliferative activities of the cannabinoids.

US Patent 6,630,507 states that certain cannabinoids can have useful therapeutic effects, which are not mediated by cannabinoid receptors, and are therefore not accompanied by psychoactive side effects. Furthermore, the absence of psycho-activity in some cannabinoids allows for very high doses to be used without encountering unpleasant side effects or potentially dangerous complications.

In October 2009, we confirmed that the 14,500 µgm / ml of non-psychoactive THCa was potently active in modulating the immune system and was tolerated because the 90 µgm / ml of free THC does not cross the CB1 stimulation threshold. This has supported widespread interest in juicing the whole plant, diluting that juice 10:1 for palatability and then consuming the juice in divided doses up to 5 times / day. We have discovered that dietary leaf therapy is a gradual process that increases over the first two months or regular use. Once the plant is absorbed, cannabinoids clear in 50 minutes supporting a q3-4 hour dosing."


''Cannabinoids, Terpenes and Flavinoids have numerous functions, but play a central role in modulating the immune system. They have been shown to be effective as anti-oxidants, analgesics, and as an anti-inflammatory; they are anxiolytic, effective in treating OCD, are active in cellular glucose metabolism, and appear to inhibit aggressive tumor cell growth. The terpenes are known to act synergistically as allosteric modulators at the CB2 receptor. Abnormal function of the ECS can arise from a Clinical Endo-Cannabinoid Deficiency (CECD), from an as yet unidentified Endogenous Terpene Deficiency, as well as from structural / functional deficits in the synthetic, import and degradative enzymes.''


"Every body needs access to this plant; but people with nothing else, at least this would give them their health back. Relax them, and help them enter a state of mind where they are more creative, more open to the changes they're facing; less fearful about what that means. And maybe, even offer them a sense of peace and hopefulness about what is next. Rather than focusing on what you have lost.
For places that don't have adequate vaccine, that are impoverished, this is a cheap way they can protect their bodies - and also one of the best ways they can do both at the same time.

Cannabis is one of the major plants used throughout time, it is so often overlooked, when people talk about medicinal plants of the past, people don't realize how important of a role it has played, and that compared to the whole of Human existence, it is only very recently that has had a negative stigma attached, or that is has been illegal... - compared to the whole of Human existence.

I think William is right: that we should all be writing Obama a letter thanking him for the government patent on Cannabidiol... and urging him to allow us Medical Freedom." — Kristen Courtney



Online Resources:

Sproutable raw viable pure CBD Hemp seeds are available from Suma, Detox Your World, The Happy Health Company, Biona, Hempiness, Haiths, and hempo. 

Hempo brand is shipped to any state or country, from hemping dot com, under Food. Thier seed is a dioceous, short flowering viable Russian cultivar Bialobrzeskie. B. is used for food seed or essential oil, has 1.75% CBD and 0.02% THC, but may have pheno (morphism in high UV areas) with 4% CBD to 0.34% THC!

CBD nutraceutical extracts may be sold by vendors claiming to have a product legal in all 50 states, to have been tested to contain medicinal properties; but the only way to know there aren't contaminats like an exceeding % of THC, lead and arsenic (from industrial chinese import) is standardized reporting.
Medicinal Hemp Association is the first group to regulate CBD (and other cannabinoid products) with their detailed reporting standards checklists for each supplier.

Import Netherland hemp juice: www.sanahempjuice.com

Online MMJ Vendor:

Magnesium Chloride:


Food Grade UK Hemp Leaf Tea (search):UK Google search for hanf natur hemp tea

Fine Hemp Seed oil vendors:
www.hippiebutter.com may be the cheapest USA vendor of high quality in small amounts
www.nutiva.com may be the cheapest USA vendor of high quality in large amounts

OTC Hemp CBD now legal in USA:
http://www.dixiex.com 25 mg "scripts" may contain 1 mg THC

Swiss hemp essential oil:
www.thehempshop.co.uk/product-124.htm fine Hemp essential oil


Edible 100% non-toxic Hemp root:

Video of juicing process: http://youtu.be/TWcdkl93a5w



Cited Links:













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